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Hb, the main cytoplasmic protein in RBC, is extremely important for erythrocytes primary function, as a gas exchanger and for performing oxygen (O 2 ) distribution to body tissues

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Crucially, the progress and accessibility of potent, brain-permeable compounds that specifically target 7nAChR receptors, including agonists, allosteric agonists, partial agonists, and positive modulators, would greatly aid in conducting pre-clinical and clinical trials [48]

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