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Regulation of Inflammation by Selenium and Selenoproteins: Impact on Eicosanoid Biosynthesis

NRG-GI008

(Stimulated Egr-1 gene, NAB2, FAK-paxillin and JAK-2 pathways) BPC-157 Uses ORAL: 250-500 mcg by mouth daily in 1-2 divided doses SUBQ: 250-500mcg subcutaneously once-twice daily INTRAMUSCULAR: 250-500mcg as close to the site of injury as possible QD-BID SUBLINGUAL: 200-500 mcg between cheek and gum daily in 1-2 divided doses BPC-157 used to treat injuries We will use the ACL tendon in the knee as an example for this article

DOI Smith EC, Skalski RJ, Johnson GC, Rossi GV

The D-2-naphthylalanine (D-2-Nal) at position 3 a bulky, non-natural amino acid provides critical receptor binding contributions and contributes to selectivity