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Marklund, S.L., Holme, E

FDA-identified safety concerns

For acute ischemic stroke (AIS) cases, the use of IV recombinant Tissue Plasminogen Activator (IV-rTPA) significantly improves outcome and decrease long-term disability

On the other hand, exosomes from cells with reparative potential, such as bone marrow mesenchymal stem cells (MSCs) or amniotic epithelial cells, have been found to downregulate the pro-ferroptotic lipid metabolism enzyme ACSL4, or upregulate parallel anti-ferroptosis pathways like FSP1/GPX4, thereby attenuating ferroptosis and promoting cartilage repair (Wang Y

Kieliszek M, Baejak S, Bzducha-Wrbel A, Kurcz A (2016) Effects of selenium on morphological changes in Candida utilis ATCC 9950 yeast cells