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Mitochondrial ROS production usually occurs in the early stage of cell injury, which can lead to destruction of the cell membrane of the alveolar epithelial cells and inactivation of surfactant, thus increasing membrane permeability, leading to increased leakage of proteins into the alveoli during lung injury (Alwazeer et al., 2 cannot easily penetrate mucus plugs

doi:10.1016/j.ctim.2020.102533

VEGF is induced using multiple classes of antidepressants at time points consistent with the induction of cell proliferation and therapeutic action of these treatments [297,298]

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