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Utilizing instruments such as the ADAS-Cog and the Hopkins Verbal Learning Test, the primary objective of the study was to evaluate the cognitive improvements, as well as the safety and tolerability of the treatment ( Table 3 Clinical trials of nanoparticles for treatment of neurodegenerative diseases

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3b) showed severe histopathological changes which are consistent with cardiotoxicity manifested as scattered chronic inflammatory cells with focal fragmentation of myocardial fibers and loss of nuclei (arrowhead)

This work was partly supported by grants from the Uehara Memorial Foundation and Takeda Science Foundation