Because longterm human studies are lacking, there are concerns about unknown immune, cardiovascular, or proliferative effects, and some experts warn that users may face unpredictable risks, especially with unsupervised use
A paper by by Pickart et al
FOXO4-DRI was designed to disrupt this interaction, allowing p53 to activate programmed cell death in senescent cells during laboratory studies
[DOI] [PubMed] [Google Scholar] 105.Gao L., Mao Q., Cao J., Wang Y., Zhou X., Fan L
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