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Its interaction with multiple melanocortin receptors supports investigations into neuroendocrine signalling, receptor selectivity, and peptide structure-function relationships under controlled experimental conditions

Limitations include small sample sizes, lack of large multi-center trials, all studies from Eastern Europe or Asia

Familial hemiplegic migraine type 2 is linked to the loss of function mutations of astrocytic Na + /K + ATPase which leads to an abnormal regulation of interstitial K + and glutamate

However, methylprednisolone hypothetically decreased the formation of new blood vessels and may not have significantly affected early functional recovery

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