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Forkhead box protein O4 (FOXO4) is an anti-apoptotic transcription factor which is upregulated in some senescent cells and prevents cell death by sequestering the nuclear protein p53 (70)

(2024a) described the administration of betaine alone to group II, also known as the betaine-treated group, at a 1000-mg/kg body weight per day intraperitoneally

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