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taVNS and transcutaneous auricular nerve field stimulation (PENFS) differ in their targeting of the vagus nerve due to differences in electrode design and frequency parameters, which affect the efficacy (4, 23, 25)

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doi: 10.3389/fphar.2026.1783888 Received 08 January 2026 Revised 23 February 2026 Accepted 23 March 2026 Published 15 April 2026 Volume 17 - 2026 Edited by Jos Roberto de Oliveira Ferreira, Universidade Estadual de Cincias da Sade de Alagoas, Brazil Reviewed by Ruolan Li, University of Electronic Science and Technology of China, China Ramoji Kosuru, Versiti Blood Research Institute, United States Updates Copyright 2026 Scenna, Bej, Cesare, Persichitti, Cimini, DAngelo and Castelli