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For a standard protocol using 150mcg five times weekly, a 5mg vial reconstituted in 2.5ml provides approximately 66 doses, more than enough to complete within the recommended timeframe

J Am Acad Child Adolesc Psychiatry

These include prodrug strategies, nanotechnology-based delivery systems, conjugation with different polymers (e.g., PEG), encapsulation with the use of metalorganic frameworks, targeted delivery using ligand conjugation (e.g., peptides and antibodies), or manufacture of inhalable devices (e.g., intranasal administration)

They can also help expectant mothers build up their supply of Vitamin B9 (Folate) to reduce the risk of neural tube defects like spina bifida