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This homeostatic modulation, rather than directional stimulation, suggests a fundamentally different mechanism than most vasodilators

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Since we were focused on protecting retinal neurons, which are also protected by the blood-retinal barrier, our first questions were whether the peptide could reach these cells when delivered via the blood, and whether it would be safe for the animals. To test HDAP2s safety, mice were given different doses for 14 days

Gene therapy by skeletal muscle expression of decorin prevents fibrotic disease in rat kidney