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Additionally, patients on medications that affect liver enzymes, particularly those that are substrates, inhibitors, or inducers of cytochrome P450 enzymes, should be monitored for changes in drug efficacy or side effects, as glutathione may influence liver metabolism and thus the pharmacokinetics of these drugs

doi: 10.1128/CMR.00074-20 226 RadtkeK

However, that energy effect is only true to the extent that they were B12 deficient in the first place

Proc Natl Acad Sci USA 104: 13268-13272

Peters M, Muller AM, Rose-John S (1998) Interleukin-6 and soluble interleukin-6 receptor: direct stimulation of gp130 and hematopoiesis