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They usually occur in the initial phase of starting the treatment or during dose escalation, but improve over time

The free radicals attack the phospholipids and cause their peroxidation and the antioxidant activity of the cell is drained in mitigating these reactions 33,77,78

Apoptosis, primarily mediated by caspase-dependent mechanisms, can be initiated through the extrinsic death receptor or the intrinsic mitochondrial pathway

Prescriptions are reviewed by licensed providers and filled by independent pharmacies

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