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This excellent safety record contributed to the peptides characterization as having tolerability indistinguishable from placebo in published research

It is also worth being explicit about what documented means here, because it is the load-bearing word for a YMYL page

If a pregnant patient has a documented deficiency of one or more B vitamins or a condition like hyperemesis that prevents oral intake, the benefits of correcting the deficiency (preventing serious maternal and fetal complications) outweigh any minimal risk from the injection

Patients on Specific Medications: Certain medications, like proton pump inhibitors or metformin, can interfere with B12 absorption, making monitoring and supplementation necessary