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Our findings, which utilize a novel CSMN reporter line with TDP-43 pathology, not only reveal the presence of metabolomic defects at an early stage of the disease, but also suggest that proper modulation of metabolomic imbalance could offer therapeutic strategies to improve the integrity of mitochondria, and thus the health of diseased UMNs

ISBN 9780071481274

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High prevalence of infertility among women with graves Disease and hashimotos thyroiditis

Cysteine, homocysteine, and mitochondrial dysfunction The interplay among cysteine, homocysteine, and mitochondrial dysfunction is intricate, involving diverse biochemical processes