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The IC 50 of SU11274 was between 1 and 2.5 mol/L and apoptosis was observed in five melanoma cell lines that expressed c-Met [65]

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The initial indication that G0S2 was involved in lipolysis was from studies showing that G0S2 mRNA expression is highest in WAT and BAT, upregulated during adipocyte differentiation (51), and a peroxisome proliferator-activated receptor (PPAR) target gene