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It stimulates collagen and elastin synthesis through cellular signaling rather than requiring increased protein substrate availability

This interaction stimulates collagen production, which is vital for maintaining skin elasticity and firmness (1)

This, in turn, has been demonstrated to result in the up-regulation of PD-L1 expression, the reduction of CD4 and CD8 T-cell activation and tumor infiltration, and the promotion of the growth of pancreatic ductal adenocarcinoma (PDAC) cells [112]

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