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Kathmandu Univ Med J (KUMJ) (2014) 12(46):1326

In practice, clinicians should start with the evidence-backed dosing (e.g

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Key aspects of the dosing protocol include: Initial treatment starts with 1ml weekly for 4 weeks [9] Frequency may range from 1-3 times per week based on individual needs [1] Dosage may increase to 2ml per week or 1ml twice weekly depending on results [9] Water-soluble nature allows safe administration 1-2 times weekly [10] Some practitioners may recommend B12 shots up to twice per week specifically for energy enhancement and improved fat metabolism [11]