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(2004) demonstrated that epithalamin can increase melatonin production in healthy elderly human subjects, via the peptides modulation of the pineal glands melatonin-producing function [7]

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[176] Prolonged elevations of brain temperature above 40 C likely promote the development of amphetamine-induced neurotoxicity in laboratory animals by facilitating the production of reactive oxygen species, disrupting cellular protein function, and transiently increasing bloodbrain barrier permeability