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10.3748/wjg.v24.i48.5462 30 DuplancicB.StambolijaV.HoljevacJ.ZembaM.BalenovicI.DrmicD.et al (2014)

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Cell Biol

Regulatory background and milestones referenced in published literature Data summarized from documented research programs Documented research applications and signaling behavior Evaluated for central signaling Source Studied in diverse research models Source Defined signaling duration Source Alternative to peripheral agents Source Literature indicates that PT-141 activates melanocortin receptors in the hypothalamus, focusing on the neurological signaling associated with appetite and motivation