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This lack comes with a laundry list of truly awful symptoms, including accelerated ageing and a higher risk of diabetes, and heart, lung, and liver diseases

Since B12 is required for both the methionine synthase reaction and the methylmalonyl-CoA mutase reaction a megaloblastic anemia resulting from B12 deficiency is also associated with an accompanying methylmalonic acidemia, whereas megaloblastic anemias caused by folate deficiency are not

Karin, "ER Stress Cooperates with Hypernutrition to Trigger TNF-Dependent Spontaneous HCC Development", Cancer cell , 2014 , 26 (3), 331

Both are once-weekly subcutaneous injections, but only one has an approved dosing schedule

Desensitization to co-trimoxazole (trimethoprim-sulphamethoxazole) in HIV-infected patients: is patch testing a useful predictor of reaction