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Psychosis secondary to thyrotoxicosis: an educational review

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Am J Physiol 290(4):G747G756 Shimomura Y, Harada M, Goto M, Sugo T, Matsumoto Y, Abe M et al (2002) Identification of neuropeptide W as the endogenous ligand for orphan G-protein-coupled receptors GPR7 and GPR8

Most importantly, because mouse proteins are foreign to the human immune system, a human anti-mouse antibody (HAMA) response is elicited resulting in a rapid clearance of the mouse antibody and adverse reactions