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While severe hypoglycemia is uncommon with tirzepatide monotherapy due to its glucose-dependent mechanism, combining it with other glucose-lowering agents or supplements increases risk

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References Abdalrahman SS, Smail HO, Shallal AF

Cirrhosis and hepatocellular carcinoma Hepatocellular carcinoma Hepatocellular carcinoma (HCC) typically arises in a chronically diseased or cirrhotic liver and is the most common primary liver cancer

Furthermore, the pathogenesis and elevated risk of certain inflammatory processes, including obesity, are related to dysbiosis