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While most stick to the standard ten-pack format, a few vary slightly in how they pack and present their products

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In fact, one vaping pod or disposable vape has the equivalent of about 1 pack/20 cigarettes, so it is possible that frequent e-cigarette users may end up smoking more than a traditional cigarette smoker

This results from a tyramine-induced depletion of norepinephrine normally present in the readily releasable vesicle pool, and replacement of vesicular norepinephrine with tyramine (which functions as a false- or pseudo- neurotransmitter), which when released has no effect on postsynaptic adrenergic receptors (Figure 1)