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Many people with LPR do not report classic heartburn but do have throat symptoms that flare after eating or when lying down

The GG genotype lowers homocysteine but raises risk for: Systemic lupus erythematosus Bipolar disorder Schizophrenia Congenital facial and spinal malformations Down syndrome Methionine Synthase Reductase: An AG substitution at base pair 66 affects ~ 30% of individuals

2023;237(Pt 1):116843

GSH peroxidase inactivates peroxides, using GSH as its cofactor to convert lipid peroxides to less harmful hydroxylated fatty acids, water, and GSH disulfide

This specific structural arrangement allows glutathione to serve as the ultimate biochemical shield, constantly sacrificing its own electrons to neutralize highly destructive, electron-stealing molecules known as free radicals, as detailed in comprehensive biochemical reviews