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Short answer: If you can absorb B12, high-dose oral B12 (1,0002,000 mcg/day) is as effective as intramuscular injections for normalizing levels in most people (AAFP

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Egr-1 stimulation supports vascularization and reduces ischemic tissue damage, according to preclinical research

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The vitamin is also essential for DNA synthesis and red blood cell formation, meaning deficiency can have wide-ranging effects beyond the nervous system, including fatigue and cognitive difficulties

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Preliminary research suggests that these mechanisms may be similar to those observed with exogenous hGH therapy, including the activation of the adrenergic receptors and increased lipolysis in adipocytes [5]

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