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[PubMed] [Google Scholar] 185.Zini A., De Lamirande E., Gagnon C

Microglial activation reduction: Retinal microglia (resident immune cells) become activated in disease states releasing inflammatory mediators and reactive oxygen species

Previous work has shown that the abundance of Lactobacillus reuteri (normalized to a control group) decreases during the onset of obesity and remains suppressed even after dieting in mice 99 , which parallels our observations that vehicle-treated diet-switched mice had lower levels of Lactobacillus than the 5A-1MQ-treated mice, the latter of which also demonstrated greater weight loss

Although the previous studies indicated the therapeutic effects of migraine supplementation, more RCT studies are required to define the best dose and duration of omega-3 supplementation for migraine patients

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