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This drug and dosing regimen has demonstrated efficacy in non-human primates after high-dose radiation therapy (Farese 2012) and, as of this writing, Extimia is being evaluated in an open-label randomized phase II clinical study (BCD-017-2), which is expected to conclude in 2013 (ClinicalTrials.gov 2012a)

These results are also in agreement with earlier reports 44, 52

Congress intended for the FDA to refer to a substantive body of evidence about the safety and effectiveness of ingredients put on the bulks list, she said

Clinical implications Recognizing RS as a potential adverse effect of antioxidant therapy has important therapeutic implications for the clinical management of male infertility [14]

As the Australian Dental Association highlights, "As scientific evidencebased guidelines, their greatest value is being kept up to date" [1]