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If the agency is sued, he added, "we strongly believe this will hold up under any legal challenges." Reynolds American, maker of Camel and Newport cigarettes, said it supports public awareness efforts on tobacco, "but the manner in which those messages are delivered to the public cannot run afoul of the First Amendment." Reynolds was one of five tobacco companies that challenged the FDA's original warning labels

This story was reported from Washington, D.C.

No significant differences were found in the IL-10 or TGF- levels in the TNBS group following smoke exposure or in the IL-17 or IL-6 levels in the DSS group