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Within experimental models, it is commonly investigated for its interaction with NNMT-associated pathways and molecular signalling mechanisms

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[DOI] [PMC free article] [PubMed] [Google Scholar] Mingione V

Side Effects and Safety Side effects Across preclinical studies and the small human trials published to date (~28 subjects across pilot studies), the reported adverse events stay limited: Mild injection-site irritation (rare) No systemic toxicity at therapeutic doses in published reports Oral administration: mild GI upset in sensitive individuals No immunosuppression, hormonal disruption, or metabolic side effects have been observed