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Parseghian CM, Sun R, Woods MN, Napolitano S, Alshenaifi J, Willis J, Nunez SK, Sorokin A, Marie PK, Singh Raghav KP, Morris VK, YC Shen JP, Sanchez EV, Rehn M, Ang A, Troiani T, Kopetz S

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BPC-157 even at 1000x therapeutic doses shows minimal toxicity in animal studies

Clinical studies on this ingredient showed no irritation, sensitization, or phototoxicity

Melatonin exerts protective effects in an ILC2-biased model of allergic airways disease, even in the presence of canonical receptor blockade To determine whether the protective effects of melatonin extended beyond allergen-driven disease, we next employed an ILC2-biased IL-33 model of allergic airways inflammation ( Figure 2A )