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doi: 10.1186/s12885-018-4824-5 70

The authors identified an autosomal recessive juvenile parkinsonism gene located on chromosome 6 as the parkin RING-finger ubiquitin ligase and multiple classes of deletion mutants in the gene

Starting with larazotide, its primary effect is to prevent inflammation from occurring in the first place by improving intestinal barrier function

Lixisenatide reduces amyloid plaques, neurofibrillary tangles and neuroinflammation in an APP/PS1/tau mouse model of Alzheimers disease

NRF2-mediated regulation of ferroptosis NRF2, encoded by the NFE2L2 gene, is precisely regulated by the E3-ubiquitin ligase system [83,84,85]