The rate-limiting step in the de novo synthesis of the GSH is catalyzed by gamma-glutamyl-cysteine synthetase (also known as glutamine-cysteine ligase), which is a target gene of Nrf2
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Ascorbate peroxidases originally engineered for electron microscopy (Rhee et al., 2013
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Once metabolized, NAC's sulfhydryl group interacts with the disulfide bonds in mucoprotein
