10.1038/ng0595-111
Targeting pathways that can regulate tumor cell ferroptosis is an emerging antitumor strategy because malignant tumor cells usually rely on oncogenic and survival signals, making them particularly vulnerable to ferroptosis
Selepe MA, Kunyane P, Seboletswe P, Nair S, Cele N, Engelbrecht M, Joubert DF, Vandevoorde C, Singh P, Sonopo MS (2022) Synthesis and evaluation of benzoylbenzofurans and isoflavone derivatives as sirtuin 1 inhibitors with antiproliferative effects on cancer cells
Residues 14 were disordered in all structures along with loop residues 133135 in C1-31
Results Retrieved studies for the meta-analysis of GSH The literature search identified a total of 8 studies involving 230 patients (mean age of 27, 43.5% male) and 216 healthy volunteers (mean age of 31.5, 42.8% male)