O'Hollaren detailed the effective use of IV-infused NAD+ for the prevention, relief, or treatment of acute and chronic symptoms of addiction to a range of substances, including alcohol, heroin, opium extract, morphine, dihydromorphine, meperidine, codeine, cocaine, amphetamines, barbiturates, and tranquilizers (18)
There is evidence that the peptide restricts NNMT function, improving fat-burning
Unfortunately, chances are that vitamin B12 deficiency has already harmed your nerves by the time you experience symptoms
NNMT inhibition reduces consumption of nicotinamide (and of S-adenosylmethionine) by blocking the enzyme that would otherwise methylate them
WS patient samples and WS animal models' NAD+-deficient cells showed impaired mitophagy (selective degradation of defective mitochondria) (25)