However, Lauridsen et al
It enters circulation and activates the same gene expression cascades throughout the body affecting collagen synthesis in skin, wound healing in connective tissue, and potentially neuroprotection in the nervous system
BSO is an inhibitor of GSH synthase that has been used to deplete GSH in vitro , including in macrophages ( We analyzed the gene expression profile and identified patterns of LPS-induced genes that were inhibited by endogenous GSH or that, on the contrary, required GSH for their induction

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