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Raun et al

While it is known that skin cells can produce estrogens locally, aromatase enzyme activity is dramatically reduced to approximately 30 times lower than in premenopausal ovarian follicular tissue [10]

The medical ethics committee of the Hospital Network Antwerp (ZNA, approval numbers 2805 and 2806) granted the ethical approval and the study was compliant with the World Medical Association Declaration of Helsinki on Ethical Principles for Medical Research Involving Human Subjects

[DOI] [PubMed] [Google Scholar] 94.Wink DA, et al

Towards understanding the biology of premenstrual dysphoric disorder: From genes to GABA