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The 28-day rule Once reconstituted, semaglutide should be used within 28 days

doi: 10.1016/j.bbadis.2013.04.007 169 ShihAYJohnsonDAWongGKraftADJiangLErbHet al

The main reason is that GSH-Au NCs@His does not have the capacity to form an Au-S bond, which greatly reduces the effectiveness of GSH-Au NCs@His to consume GSH, thus protecting tumor cells from ROS oxidative damage (Figure 7C)