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Centers for Disease Control and Prevention (CDC), Current Cigarette Smoking Among Adults in the United States, 2019, data_statistics/fact_sheets/adult_data/ cig_smoking/index.htm

The FDA needs to monitor if users are indeed switching completely to IQOS to justify the reduced exposure claim

This was somewhat surprising since E-cig exposure alone resulted in a significant increase in macrophages compared to air exposure

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Access to Cessation Resources: Ensure access to evidence-based tobacco cessation resources, including counseling, medication, and support services, for individuals who want to quit smoking or using other tobacco products