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Therefore, it isnt uncommon to see tesamorelin given as an off-label prescription for weight loss or muscle growth

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The report was uncontrolled, unblinded, not randomized, had no comparator arm, used patient-reported outcomes rather than validated pain instruments, and did not publish dose, effect size, confidence intervals, p-values, or systematically collected adverse events limitations that severely constrain any clinical inference

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Supporting neurotrophic signaling through lifestyle strategies may help reinforce these pathways