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Initial studies found that ATXN3 interacts with 2 proteins: HHR23A and HHR23B that are both homologs of the DNA repair protein Rad23 [98] and with ubiquilin (UBQLN)-2 [99]

This multi-pronged action is exactly why researchers and dermatologists keep studying them

Prado et al ., 2024, "Muscle matters: the effects of medically induced weight loss on skeletal muscle"

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Key Benefit NAC primarily works as a building block for glutathione production