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Long-term corticosteroid use is associated with bone loss and increased risk of fracture

Regarding anticancer activities, catalpol underwent pyrazole heterocyclic modification at the C10-position hydroxyl group, yielding derivatives that demonstrated strong inhibitory activity against esophageal cancer cells (Kong et al., 2023a)

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Because TSP and OCM are central in many metabolic processes, such as methylation, GSH production, amino acid metabolism, and H 2 S production, the enzymes and metabolites may represent potential candidates for therapeutic targets