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[10] [12] High-dose ascorbic acid may diminish the therapeutic effects of certain chemotherapeutic agents, such as bortezomib, due to its antioxidant properties

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The stimulant category also includes phenethylamines and derivatives, which have been used in concentrated forms as supplement ingredients but also are widely present naturally in plants and are used as flavoring additives

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It reflects deeper biological processes hormones, inflammation, sun exposure, and internal balance