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Perceived exertion was lower at 8 min ( p = 0.042), 9 min ( p = 0.035), 10 min ( p = 0.043), 11 min ( p = 0.028), 12 min ( p = 0.028), and 13 min ( p = 0.018) when compared to the placebo, suggesting that LC supplementation reduced the mental and physical strain during high-intensity exercise (Fig

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Signal Transduct Target Ther 2 Mahdavi AM, Mahdavi R, Kolahi S, Zemestani M, Vatankhah A-M (2015) L-Carnitine supplementation improved clinical status without changing oxidative stress and lipid profile in women with knee osteoarthritis

Phase II Clinical Trials These promising preclinical findings led to Phase I and Phase II clinical trials in humans