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The relevancy of tested concentrations in APAP-CYS and PAP-CYS can be supported by the levels of APAP-CYS occurring in humans at x.10.micromolar range during 210 h after APAP overdose (Curry et al

0.1750 g/mL) accumulated within and diffused through intestinal structures, leading to an increased contractile response, most notably at a concentration of 10 g/mL

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