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IGF-I signaling is important in skeletal muscle maintenance and repair IGF-I can reverse various muscle wasting conditions in experimental models The potential therapeutic effect of novel IGF-I formulations and biodegradable IGF-I variants must be explored in clinical trials Acknowledgements This work was supported by the project for the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD)

10.4103/0971-6580.84267 49 SongH.-Y.El SheikhaA