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A recent study demonstrated that, under heat stress, HSC70 robustly directs GPX4 to CMA, thereby promoting ferroptosis through a marked reduction in GPX4 levels in liver cells (Wang T

To, K., Cao, R., Yegiazaryan, A., Owens, J., Nguyen, T., Sasaninia, K., Venketaraman, V

They act on different appetite pathways cagrilintide is a long-acting amylin analog, while tirzepatide is a dual GIP/GLP-1 receptor agonist which is the theoretical reason researchers discuss pairing them