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Inconsistent Mendelian results and the disappearance of associations following multivariate adjustments suggest that potential confounding factors, such as smoking, educational attainment, and alcohol consumption, may have undermined the genetic evidence supporting causality

Melatonin forms stable metabolites which are also free radical scavengers, resulting in a free radical scavenging cascade, unique only to melatonin

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2007 Jul 28;7(1):43-8

Region specific mitochondrial impairment in mice with widespread overexpression of alpha-synuclein