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Development of auto-antibodies Some cobalamin preparations in rare cases can stimulate an allergenic response where there is development of antibodies to the cobalmin injected

The effects of a single B12 injection typically last one to two weeks, though this varies depending on your baseline levels, metabolism, and overall health

The clinical significance of this difference for most patients is debated, and for the majority of people either form is adequate

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[6] Children in some regions of developing countries are at particular risk due to increased requirements during growth coupled with diets low in animal-sourced foods