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The PPI network was visualized using the Cytoscape 3.2.1 software ( Imaging Phase contrast imaging was performed on the EVOS Cell Imaging System (Thermo Fisher Scientific)

Chemicals and Reagents Amodiaquine dihydrochloride was obtained from ICN Biomedicals (Aurora, OH, United States), DEAQ was obtained from BD Biosciences (Franklin Lakes, NJ, United States)

It modulates GABA receptors allosterically, influences dopamine and serotonin receptor activity, enhances enkephalin levels, and reduces neuroinflammation, all through a single compound

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